Evaluating the Effect of Mentha piperita Extract on Lipid Profile and Blood Glucose Level of Lead- induced Toxicity Rats

Objectives: The aim of the present study was to investigate the effect of mentha piperita extract on the levels of triglycerides, cholesterol, and blood glucose in experimental rats following lead intoxication for five weeks period. Methods: Thirty experimental male rats were divided into one control group plus four groups with lead-induced toxicity, then the levels of cholesterol, triglyceride, and blood glucose were measured after administration of mentha piperita extract in two doses, 500mg/kg and 1000mg/kg. Results: Mean cholesterol, triglycerides, and blood glucose levels in lead-induced toxicity rats were: 5.29?0.41mmol/L, 1.79?0.16mmol/L 1.20?0.22mmol/L respectively, which shows significant (p<0.05) reduction in triglycerides levels following administration of mentha piperita extract at dose 1000mg/kg. Conclusions: The therapeutic use of Mentha piperita extract was proved to be effective in reducing the plasma triglycerides levels in lead-induced toxicity rats, while there is no significant alteration in the concentration of blood glucose and cholesterol levels following administration of Mentha piperita extract