Glucose/Fe-doped C70 fullerene hybrid biosensor: theoretical study

AbstractThe interaction between glucose molecule and C70 fullerene (pristine and Fe-doped) was investigated with the aid of density functional theory. Our results provide useful information that uncover the chemical and biological activities of C70 when interact with glucose molecule. To mimic real situations, all possible configurations of glucose with respect to fullerene were investigated under both vacuum and distilled water mediums. As expected, no significant change in the calculated energy gaps for all pristine configurations regardless the simulated medium, which indicates that the interaction between glucose molecule and pristine Fullerene is weak physisorption. However, doping fullerene with Fe atom significantly reduced the energy gap for all configurations of the complex which in turn offers an advantage over pristine fullerene for measuring glucose in real situations such as blood.