Green Methodologies for the Synthesis of Thiophene Chalcone Derivatives: A Review

Thiophene chalcone derivatives are synthesized using green synthetic methods, which are compiled in this review. Chalcones and their derivatives possess a wide spectrum of biological and pharmacological applications, which has led a lot of researchers to synthesize these compounds continuously, which in the process leads to the generation of a lot of waste that affects the environment. This is how environmentally friendly synthetic processes are used to reduce the use and production of hazardous organic materials. The main point of this review is to show the newest non-traditional ways that scientists and researchers have been able to make chalcones with sulfur heterocycles, specifically thiophene. The literature study on thiophene chalcone is valuable for researchers working on this heterocyclic compound synthesis, providing valuable information on green synthetic methods