Effects of Celery Leaf Aqueous Extract on Fertility and Liver Enzyme in Diabetic Male Rats: Egypt. Acad. J. Biolog. Sci. (B. Zoology) Vol. 15(2) pp:131-138 (2023) DOI: 10.21608/EAJBSZ.2023.330595
ABSTRACT
The presented study examined the potential effects of celery leaf
extract on spermatogenesis in diabetic male rats. Methodology: Twentyfour male rats total were used in the study; they were split into three groups
of eight rats each: Control group: Every day, one milliliter of distilled water
was given to normal rats. Group with diabetes: Every day, 1 ml of distilled
water was also given to diabetic rats. Group receiving celery extract: For
thirty days in a row, diabetic rats received a daily dose of 200 mg/kg of
celery extract. Results: Sperm count and seminiferous tubule diameter
were significantly higher in the group receiving 200 mg/kg of celery extract
compared to the control group. Testicular Volume and Organ Weights:
Additionally, the treated group showed a significant increase in the vas
deferens, epididymis, and testis testicular volumes and weights. Lipid
profile and glucose: Celery extract had a notable impact on glucose and
triglyceride levels in diabetic rats. Liver enzymes: The extract markedly
raised the levels of the liver enzymes aspartate aminotransferase (AST) and
alanine aminotransferase (ALT). Conclusion: These findings imply that
celery juice extract may be advantageous for a number of diabetic male rat
parameters, including spermatogenesis, liver enzymes, lipid profiles,
glucose concentrations, and reproductive parameters. This suggests that
celery may help to improve male fertility and prevent complications from
diabetes. Nevertheless, additional investigation is required to clarify the
fundamental processes accountable for these impacts and validate the
findings